Citation

Weiss B, Rothmann C, Weber M, Streiff R, Seiwert E. J. Eur. Urgences 2002; 15(4): 208-210.

Copyright

(Copyright © 2002, Masson Editeur )

DOI

unavailable

PMID

unavailable

Abstract

Very few lamotrigine acute poisonings have been reported. None of them report a correlation between the clinic and toxicokinetic features. We report a case of acute self-poisoning by lamotrigine and alprazolam. The main clinical symptoms were neurological and gastrointestinal. The peak plasma concentration was 25.3 mcg/ml, the elimination half-life was 26 hours, suggesting linear kinetics (order 1). The patient had a favorable course after supportive treatment alone.

Language: fr

Keywords

abdominal pain; Acute poisoning; adult; alprazolam; article; ataxia; case report; drug blood level; drug elimination; drug half life; female; gastrointestinal symptom; Gastrointestinal symptoms; human; lamotrigine; Lamotrigine; nausea; neurotoxicity; nystagmus; palliative therapy; priority journal; self poisoning; suicide attempt; toxicokinetics; Toxicokinetics; vomiting