Citation

Windemuth D, Bacharach-Buhles M, Hoffmann K, Altmeyer P. Hautarzt 1999; 50(4): 266-269.

Copyright

(Copyright © 1999, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s001050050899

PMID

unavailable

Abstract

Adjuvant therapy with interferon for malignant melanoma causes neurotoxic side effects such as depression. The biochemical mechanisms are unknown. We report two cases with both depression and amnesia. In one case, attempted suicide was a companied by 7 h of amnesia. The diagnostic classification and possible explanations for the amnesia secondary to interferon therapy are reviewed.

Language: de

Keywords

adjuvant chemotherapy; adult; alpha interferon; amnesia; article; case report; depression; Depression; disease classification; Germany; human; Interferon; melanoma; Melanoma; neurotoxicity; psychiatric diagnosis; recombinant alpha2b interferon; Side effects; subcutaneous drug administration; suicidal behavior; Suicidal intention