Citation

Thakurdesai A, Rivera-Matos L, Nagra N, Busch B, Mais DD, Cave MC. ACG Case Rep. J. 2024; 11(5): e01354.

Copyright

(Copyright © 2024, American College of Gastroenterology)

DOI

10.14309/crj.0000000000001354

PMID

38706451

PMCID

PMC11068125

Abstract

Fenbendazole is an anthelmintic agent approved for veterinary applications. Even though it is not approved by the US Food and Drug Administration for human use, such use appears to be increasing due to the popularization of fenbendazole's potential anticancer effects by social media. We describe the first case of histologically confirmed severe drug-induced liver injury, hepatocellular pattern, associated with the self-administration of fenbendazole in a 67-year-old woman who presented with 2 weeks of jaundice. Liver function tests normalized in 3 months after the cessation of fenbendazole.

Language: en

Keywords

drug-induced liver injury; fenbendazole; hepatotoxicity; liver biopsy; liver function tests