Citation

Krug MK, Takarae Y, Iosif AM, Solomon M. Cereb. Cortex 2024; 34(13): 1-7.

Copyright

(Copyright © 2024, Oxford University Press)

DOI

10.1093/cercor/bhae097

PMID

38696604

Abstract

Adolescence has been characterized as a period of risky and possibly suboptimal decision-making, yet the development of decision-making in autistic adolescents is not well understood. To investigate decision-making in autism, we evaluated performance on 2 computerized tasks capturing decision-making under explicit risk and uncertainty in autistic and non-autistic adolescents/young adults ages 12-22 years. Participants completed the Game of Dice Task (32 IQ-matched participant pairs) to assess decision-making under explicit risk and the modified Iowa Gambling Task (35 IQ-matched pairs) to assess decision-making under uncertainty. Autistic participants overall made riskier decisions than non-autistic participants on the Game of Dice Task, and the odds of making riskier decisions varied by age and IQ. In contrast, the autistic group showed comparable levels of learning over trial blocks to the non-autistic group on the modified Iowa Gambling Task. For both tasks, younger autistic participants performed poorer than their non-autistic counterparts, while group differences diminished in older ages. This age-related pattern suggests positive development during adolescence on risk assessment and decision-making in autism but also implies differential developmental trajectories between groups. These findings also suggest differential performance by the risk type, with additional complex influences of IQ and fluid cognition, which warrants further investigations.

Language: en

Keywords

*Autistic Disorder/psychology; *Decision Making/physiology; adolescence; Adolescent; autism; Child; decision making; development; Female; Gambling/psychology; Humans; Male; Neuropsychological Tests; Risk-Taking; Uncertainty; Young Adult; young adulthood