Citation

Cohen J, Petitjean H, Blasco MB, Mizrahi R. Acta Neuropsyciatr. 2024; ePub(ePub): ePub.

Copyright

(Copyright © 2024, Cambridge University Press)

DOI

10.1017/neu.2023.60

PMID

38200701

Abstract

OBJECTIVES: The link between cannabis use and psychotic symptoms or disorders is well known. However, the relation between cannabis withdrawal and psychotic symptoms is less studied.

METHODS: To our knowledge, this is the first publication of an observational systematic report of cannabis-induced psychotic disorder with onset during withdrawal. Here, we review patients presenting to a major emergency room in Montreal between January 2020 and September 2023 in a context of psychotic symptoms following cannabis cessation.

RESULTS: 7 male and 1 female patients presented at the peak of cannabis withdrawal with acute psychotic symptoms, representing less than 1% of all emergency service admissions.

CONCLUSIONS: We discuss current knowledge regarding the endocannabinoid system and dopamine homeostasis to formulate hypothesis regarding these observations.

Language: en

Keywords

Cannabis; Psychosis; Withdrawal