Citation

Awad AFH, El-Zohairy EAF, El-Kady NK, Rasheed AMA, Bayoumy AAF. Egypt. J. Forensic Sci. Appl. Toxicol. 2023; 23: 111-119.

Copyright

(Copyright © 2023, Department of Forensic Medicine and Clinical Toxicology, Kasr-Alainy School of Medicine, Cairo University)

DOI

10.21608/ejfsat.2023.177423.1282

PMID

unavailable

Abstract

OBJECTIVES: The purpose of this study was to compare between the management and the outcome of typical and atypical antipsychotic drugs overdose in Egypt.

METHODOLOGY: This study was conducted on 75 cases presented to National Environmental and Clinical Toxicology research Centre, Cairo university hospitals with antipsychotic medications toxicity, from April 2018 to September 2018.

RESULTS: The most common presenting age group was age group B; from 18-40 years (45.3%), females (68%), belonging to urban population (82.7%), educated (96.2%) and not working (89.3%). The majority of cases presented with abnormal CNS manifestation; altered conscious level (97.3%), abnormal pulse; tachycardia (98.7%) and abnormal pupil size; mydriasis or miosis (52%). Most of the cases did not do drug screening (98.7%), neither do decontamination (66.7%) nor receive antidote (100%), but most of them received supportive measures. Most of the cases were admitted (90.7%) and stayed in hospital more than 24 hours and less than one week. Regarding the outcome, most of the cases were cured (92.6%).

Language: en