Citation

Thivaharan Y, Dayapala A, Thanushan M. Egypt. J. Forensic Sci. 2023; 13(1): e9.

Copyright

(Copyright © 2023, Forensic Medicine Authority of Egypt, Publisher Elsevier Publishing)

DOI

10.1186/s41935-023-00327-4

PMID

36712698

PMCID

PMC9869291

Abstract

BACKGROUND: After substantial trauma, pulmonary embolism (PE) carries a high risk of morbidity and mortality. Early post-traumatic PE in the absence of deep vein thrombosis (DVT) is a distinct entity that might be connected to rare mechanisms or unidentified biochemical processes. CASE PRESENTATION: A driver of a car was presented with worsening chest pain and shortness of breath (SOB) following a road traffic accident in which he suffered an impact on the chest against the steering wheel and a closed fracture of the right femur. Radiological investigations revealed a pulmonary embolism in the left posterior segment pulmonary artery, without evidence of internal chest injuries or DVT within 12 h from the incident. D-dimer, troponin I, and creatinine kinase were elevated without evidence of myocardial infarction or myocardial injury. Other parameters were within the normal range.

CONCLUSIONS: Possibilities of early PE in the absence of detectable DVT could be due to hyper-coagulability states, clots from the lower extremity completely getting detached and embolizing to the pulmonary circulation, screening errors, and "de novo" thrombi in the pulmonary circulation. Chest trauma is an identified risk factor for early or late pulmonary embolism. Action of the post-traumatic adrenergic response causing vascular endothelial inflammation and the synthesis of circulating adhesion molecules leading to localized thrombosis have also been suggested as causes for this phenomenon. A greater understanding of rare risk factors for early PE and the possibility of rare complications of chest trauma is useful in detecting and treating them in time, reducing morbidity and mortality.

Language: en

Keywords

Chest trauma; De novo thrombi; Deep vein thrombosis; Early pulmonary embolism; Long bone fracture