Citation

Yang R, Cao Y, He D, Dang W, Qiu C, Zhang W. BMC Psychiatry 2022; 22(1): e714.

Copyright

(Copyright © 2022, Holtzbrinck Springer Nature Publishing Group - BMC)

DOI

10.1186/s12888-022-04332-0

PMID

36384487

PMCID

PMC9670649

Abstract

BACKGROUND: The agenesis of corpus callosum (ACC) could impair the connectivity of the hemispheres of the cerebral cortex and cause cognitive impairments, social and behavioral issues, and even psychiatric disorders. Although social deficits are common in ACC patients, it is rare for a social anxiety disorder to occur. CASE PRESENTATION: To report a 17-year-old adolescent with complete ACC associated with social anxiety disorder, depression, impulsive behavior, and other neurodevelopmental defects such as intellectual disabilities. His avoidance and fear were improved after treatment with sertraline.

CONCLUSIONS: This is the first report of social anxiety disorder in ACC patients. The possible relationship between brain structural abnormities and anxiety syndrome should be investigated in more studies.

Language: en

Keywords

Social anxiety disorder; Case report; Agenesis of the corpus callosum; Psychiatric disorders; Social phobia