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Journal Article

Citation

MacCarthy M, Heyn P, Tagawa A, Carollo J. Dev. Med. Child Neurol. 2022; ePub(ePub): ePub.

Copyright

(Copyright © 2022, Mac Keith Press, Publisher John Wiley and Sons)

DOI

10.1111/dmcn.15225

PMID

35366333

Abstract

AIM: To examine the relationship between quantitative gait measurements and self-reported physical, psychological, cognitive, and social function status in young adults with cerebral palsy (CP).

METHOD: Seventy-two adults with CP (range 18-48y; median age 23y [interquartile range 21-27y]; 34 males, 38 females), in Gross Motor Function Classification System levels I to IV, who previously underwent an instrumented gait analysis (IGA) at our center as children were recruited. Participants underwent a repeated IGA. National Institutes of Health Patient-Reported Outcomes Information System (PROMIS) instruments including the PROMIS-57, Applied Cognition - General Concerns (Short Form), and Applied Cognition - Executive Function (Short Form) were administered. Data derived from current and prior IGA were compared via non-parametric correlation analysis with PROMIS subscores.

RESULTS: Subscores for anxiety, depression, sleep, and fatigue did not significantly correlate with any IGA data. Walking speed, adjusted for stature, correlated strongly with multiple subscores: physical function (p<0.001, r(s) =0.708); participation in social roles (p=0.007, r(s) =0.319); executive function (p=0.005, r(s) =0.335). Pain interference correlated with longitudinal change in adjusted walking speed (p=0.032, r(s) =-0.259). The Applied Cognition - General Concerns (Short Form) correlated with prior absolute walking speed, but not adjusted values.

INTERPRETATION: This study underscores the importance of walking speed and its association with a variety of functional domains in adults with CP.


Language: en

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