Citation

Zu Eulenburg P, Buchheim JI, Ashton NJ, Vassilieva G, Blennow K, Zetterberg H, Choukèr A. JAMA Neurol. 2021; ePub(ePub): ePub.

Copyright

(Copyright © 2021, American Medical Association)

DOI

10.1001/jamaneurol.2021.3589

PMID

34633430

Abstract

Long-duration spaceflight has a widespread effect on human physiology. The past decade first revealed eyeball alterations, and then neuroimaging studies hinted at potentially detrimental effects on the brain.1,2 Expansion of cerebrospinal fluid spaces occurs at the cost of the gray and white matter compartment. A neurobiological integrity assessment of the brain's tissues after prolonged exposure to microgravity has never been conducted, to our knowledge. Therefore, we investigated the longitudinal course of blood-based biomarkers representing the brain parenchyma in long-duration spaceflight...

Language: en