Citation

Najt P, Perez J, Sanches M, Peluso MA, Glahn D, Soares JC. Eur. Neuropsychopharmacol. 2007; 17(5): 313-320.

Affiliation

MOOD-CNS Program, Division of Mood and Anxiety Disorders, Department of Psychiatry, The University of Texas Health Science Center at San Antonio (UTHSCSA), San Antonio, TX 78229-3900, USA.

Copyright

(Copyright © 2007, Elsevier Publishing)

DOI

10.1016/j.euroneuro.2006.10.002

PMID

17140772

Abstract

Impulsivity is frequently associated with bipolar disorder (BD) during manic episodes, but may also be present in euthymic bipolar patients. Aggression is an impulsivity-related behavior also found during manic episodes. The objective of this review is to further clarify the relationship between impulsivity and BD. A search in Medline and Psycinfo databases, combined with a manual search of selected references, was conducted to identify available literature on BD and impulsivity-related features. Although few studies have directly measured impulsivity in BD, available findings suggest that impulsivity is not only state-related, but also a trait component of BD, which could represent a core feature of the illness. Further research exploring the neurobiology of the impulsivity/BD relationship may contribute to elucidate the pathophysiology and to improve the diagnosis and treatment of this severe illness.

Language: en