Citation

Liu Y, Wang JZ. Zhonghua Shao Shang Za Zhi 2021; 37(2): E010.

Copyright

(Copyright © 2021, Zhonghua yi xue hui)

DOI

10.3760/cma.j.cn501120-20201125-00499

PMID

unavailable

Abstract

Severe burn can induce stress response, cause different degrees of damage to the body, and participate in the occurrence and development of immune dysfunction and hypermetabolism after burn. The rational application of analgesic and sedative drugs is the primary method of inhibiting the severe burn-induced stress response, which can alleviate the damage of tissue and organs and reduce the incidence of burn sepsis. Furthermore, integrated approaches including wound management, infection control, nutritional support, and gastrointestinal tract protection, as well as sleep management, etc., collectively contribute to the alleviation of stress response after burn injury. To further improve the success rate of severe burn treatment, it is essential to study various stress and endocrine hormones and immune pattern changes in patients with severe burn injuries, to explore the mechanism and regulation of hypermetabolism after burn, and to reach a consensus on sedation and analgesia management, the regulation of stress response and hypermetabolism after severe burn.

Language: zh

Keywords

Burns; Stress; Metabolism; Analgesia; Sedation