Citation

Bertsch K, Florange J, Herpertz SC. Curr. Psychiatry Rep. 2020; 22(12): e81.

Copyright

(Copyright © 2020, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s11920-020-01208-6

PMID

33180230

Abstract

PURPOSE OF REVIEW: To review the current literature on biobehavioral mechanisms involved in reactive aggression in a transdiagnostic approach.

RECENT FINDINGS: Aggressive reactions are closely related to activations in the brain's threat circuitry. They occur in response to social threat that is experienced as inescapable, which, in turn, facilitates angry approach rather than fearful avoidance. Provocation-induced aggression is strongly associated with anger and deficits in cognitive control including emotion regulation and inhibitory control. Furthermore, the brain's reward system plays a particular role in anger-related, tit-for-tat-like retaliatory aggression in response to frustration. More research is needed to further disentangle specific brain responses to social threat, provocation, and frustration. A better understanding of the psychological and neurobiological mechanisms involved in reactive aggression may pave the way for specific mechanism-based treatments, involving biological or psychotherapeutic approaches or a combination of the two.

Language: en

Keywords

Emotion regulation; Cognitive control; Frustration; Frustrative non-reward; Inhibitory control; Provocation; Social threat; Threat sensitivity