Citation

Layne K, Wood DM. Medicine (Abingdon) 2020; 48(3): 211-213.

Copyright

(Copyright © 2020, Medicine Publishing)

DOI

10.1016/j.mpmed.2019.12.018

PMID

unavailable

Abstract

Opioids are among the most commonly prescribed analgesic medications, and opioid toxicity is becoming an increasing problem across the world. Patients typically present with a triad of signs: reduced consciousness, miosis and a reduced respiratory rate with shallow breaths. Patients with significant opioid toxicity are at risk of airway compromise, and basic supportive measures should be performed. Naloxone is a non-selective μ-opioid receptor antagonist that competitively binds to the μ-opioid receptor and should be administered, ideally intravenously, to patients with significant opioid toxicity.

Language: en

Keywords

Morphine; MRCP; naloxone; opiate; opioids; oxycodone