Citation

Basner M, Moore TM, Nasrini J, Gur RC, Dinges DF. Sleep 2020; ePub(ePub): ePub.

Affiliation

Unit of Experimental Psychiatry, Division of Sleep and Chronobiology, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Copyright

(Copyright © 2020, American Academy of Sleep Medicine, Publisher Associated Professional Sleep Societies)

DOI

10.1093/sleep/zsaa121

PMID

32556295

Abstract

STUDY OBJECTIVES: The Psychomotor Vigilance Test (PVT) is frequently used to measure behavioral alertness in sleep research on various software and hardware platforms. In contrast to many other cognitive tests, PVT response time shifts of a few milliseconds can be meaningful. It is therefore important to use calibrated systems, but calibration standards are currently missing. This study investigated the influence of system latency bias and its variability on two frequently used PVT performance metrics, attentional lapses (response times [RT] ≥500 milliseconds) and response speed, in sleep-deprived and alert subjects.

METHODS: PVT data from one acute total (N=31 subjects) and one chronic partial (N=43 subjects) sleep deprivation protocol were the basis for simulations in which response bias (±15 milliseconds [ms]) and its variability (0-50 ms) were systematically varied and transgressions of pre-defined thresholds (i.e., ±1 for lapses, ±0.1/s for response speed) recorded.

RESULTS: Both increasing bias and its variability caused deviations from true scores that were higher for the number of lapses in sleep deprived subjects and for response speed in alert subjects. Threshold transgressions were typically rare (i.e., <5%) if system latency bias was less than ±5 ms and its standard deviation was ≤10 ms.

CONCLUSIONS: A bias of ±5 ms with a standard deviation of ≤10 ms could be considered maximally allowable margins for calibrating PVT systems for timing accuracy. Future studies should report the average system latency and its standard deviation in addition to adhering to published standards for administering and analyzing the PVT.

© Sleep Research Society 2020. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

Language: en

Keywords

PVT; attention; calibration; sleep deprivation; sleep restriction; vigilance