Citation

Seda G, Han TS. Sleep Med. Clin. 2020; 15(1): 77-85.

Affiliation

Pulmonary Medicine Department, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA 92134, USA.

Copyright

(Copyright © 2020, Elsevier Publishing)

DOI

10.1016/j.jsmc.2019.10.001

PMID

32005352

Abstract

This article reviews the effects of obstructive sleep apnea on neurocognitive performance, proposed mechanisms of cognitive impairment, and the effects of continuous positive airway pressure on performance. Obstructive sleep apnea can affect several domains of neurocognitive performance to include attention and vigilance, memory and learning, psychomotor function, emotional regulation, and executive function. Proposed mechanisms include intermittent hypoxemia, sleep deprivation and fragmentation, hypercapnia, and disruption of the hypothalamic-pituitary-adrenal-axis. Continuous positive airway pressure can improve cognitive defects associated with obstructive sleep apnea. More data are needed to determine whether other therapies improve cognitive function.

Published by Elsevier Inc.

Language: en

Keywords

Attention; Continuous positive airway pressure (CPAP); Executive functioning; Learning; Memory; Neurocognitive performance; Obstructive sleep apnea; Psychomotor function