Citation

Miller JN, Black DW. Curr. Psychiatry Rep. 2020; 22(2): e6.

Affiliation

Department of Psychiatry, University of Iowa Roy J. and Lucille A. Carver College of Medicine, 2-126b Medical Education Building, Iowa City, IA, 52242, USA. donald-black@uiowa.edu.

Copyright

(Copyright © 2020, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s11920-020-1130-0

PMID

31955273

Abstract

PURPOSE OF REVIEW: Bipolar disorder has the highest rate of suicide of all psychiatric conditions and is approximately 20-30 times that of the general population. The purpose of this review is to discuss findings relevant to bipolar disorder and suicide. RECENT FINDINGS: Risk factors include male gender, living alone, divorced, no children, Caucasian, younger age (< 35 years), elderly age (> 75 years), unemployment, and a personal history of suicide attempt and family history of suicide attempt or suicide completion, as well as predominant depressive polarity. Suicide is associated with the depressed or mixed subtypes, not mania. Although there are emerging treatments for bipolar depression, such as ketamine and TMS, lithium remains the only medication associated with lowered suicide rates in bipolar disorder. Understanding clinical and demographic risk factors for suicide in bipolar disorder remains the best way to prevent suicidal behavior. Early intervention and treatment with anti-suicidal medications, such as lithium, along with close observation and follow-up is the best way to mitigate suicide in patients with bipolar disorder.

Language: en

Keywords

Bipolar disorder; Suicide; Suicide attempt; Suicide completion; Suicide risk factors