Citation

Paolini M, Lester D, Hawkins M, Hawkins-Villarreal A, Erbuto D, Fiorillo A, Pompili M. Medicina (Lithuania) 2019; 55(12): e55120782.

Affiliation

Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, 00185 Rome, Italy.

Copyright

(Copyright © 2019, Lietuvos Gydytoju Sajunga Lithuania)

DOI

10.3390/medicina55120782

PMID

31842504

Abstract

Background and objectives: In recent years, a growing body of research has focused on identifying possible biological markers for suicidal behavior, including infective and immunological markers. In this paper, our aim was to review available evidence concerning the association between cytomegalovirus (CMV) infection and suicide. Materials and Methods: A systematic search according to the PRISMA statement was performed on Pubmed. After the screening procedure, we identified five relevant papers. Results: We found inconsistent evidence linking CMV infection and suicide, with some papers reporting an association between CMV seropositivity and suicidal behavior, and others not finding the association. Conclusions: With the evidence available presently, it is not possible to infer whether there is a correlation between suicide and CMV infection.

Language: en

Keywords

CMV; antibodies; biomarker; cytomegalovirus; review; suicide