Citation

Wade SL, Fisher AP, Kaizar EE, Yeates KO, Taylor HG, Zhang N. J. Int. Neuropsychol. Soc. 2019; ePub(ePub): 1-9.

Affiliation

Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

Copyright

(Copyright © 2019, Cambridge University Press)

DOI

10.1017/S1355617719000778

PMID

31405391

Abstract

OBJECTIVES: We conducted joint analyses from five randomized clinical trials (RCTs) of online family problem-solving therapy (OFPST) for children with traumatic brain injury (TBI) to identify child and parent outcomes most sensitive to OFPST and trajectories of recovery over time.

METHODS: We examined data from 359 children with complicated mild to severe TBI, aged 5-18, randomized to OFPST or a control condition. Using profile analyses, we examined group differences on parent-reported child (internalizing and externalizing behavior problems, executive function behaviors, social competence) and family outcomes (parental depression, psychological distress, family functioning, parent-child conflict).

RESULTS: We found a main effect for measure for both child and family outcomes [F(3, 731) = 7.35, p <.001; F(3, 532) = 4.79, p =.003, respectively], reflecting differing degrees of improvement across measures for both groups. Significant group-by-time interactions indicated that children and families in the OFPST group had fewer problems than controls at both 6 and 18 months post baseline [t(731) = -5.15, p <.001, and t(731) = -3.90, p =.002, respectively, for child outcomes; t(532) = -4.81, p <.001, and t(532) = -3.80, p <.001, respectively, for family outcomes].

CONCLUSIONS: The results suggest limited differences in the measures' responsiveness to treatment while highlighting OFPST's utility in improving both child behavior problems and parent/family functioning. Group differences were greatest at treatment completion and after extended time post treatment.

Language: en

Keywords

Behavior; Brain injury; Parent; Pediatric; Profile analysis; Randomized controlled trial; Treatment