Citation

Zhao J, Lucassen PJ, Swaab DF. Biol. Psychiatry 2019; ePub(ePub): ePub.

Affiliation

Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands. Electronic address: d.f.swaab@nin.knaw.nl.

Copyright

(Copyright © 2019, Elsevier Publishing)

DOI

10.1016/j.biopsych.2019.04.015

PMID

31227102

Abstract

Over the past decade, pioneering studies have reported changes in various genes and proteins in postmortem brain samples of major depressive disorder (MDD) patients [e.g., (1–14); see also (15–17)] (Table 1). Even though clear inferences were made based on these results regarding underlying disease mechanisms, the results differ clearly between different studies, often even in opposite directions, and even if the patient groups had been carefully matched for factors like age, sex, and postmortem delay

Language: en