Citation

Tekin YK. Am. J. Emerg. Med. 2019; ePub(ePub): ePub.

Affiliation

Sivas Cumhuriyet University, Faculty of Medicine, Department of Emergency Medicine, Sivas, Turkey. Electronic address: yktekin@hotmail.com.

Copyright

(Copyright © 2019, Elsevier Publishing)

DOI

10.1016/j.ajem.2019.06.022

PMID

31227422

Abstract

BACKGROUND: To investigate the role of fetuin-A as a potential biomarker for prognosis of fatality in patients with carbon monoxide (CO) poisoning.

METHODS: In a prospective study, 60 poisoned patients with CO who were admitted to the department of emergency medicine between August 2017 and April 2018 were compared to 40 paired control subjects from the same department.

RESULTS: Fetuin-A levels were significantly lower in the patients with CO poisoning, especially in those non-survive (68.9 ± 7.6 vs 59.5 ± 4.1, p = 0.019). The area under the curve in the ROC curve analysis for the fetuin-A was 0.914 with a cut off of 61.15 mmol/L.

CONCLUSIONS: The decrease of Fetuin-A may indicate an early signal for the progression of fatality due to CO poisoning.

Copyright © 2019. Published by Elsevier Inc.

Language: en

Keywords

Carbon monoxide poisoning; Emergency department; Fetuin-A