Citation

Feng X, Provenzano F, Appelbaum PS, Masucci MD, Brucato G, Lieberman JA, Girgis RR. Psychiatry Res. Neuroimaging 2019; 287: 60-62.

Affiliation

Columbia University, Department of Psychiatry, New York State Psychiatric Institute (NYSPI), 1051 Riverside Drive, Unit 31, New York, NY 10032, USA. Electronic address: ragy.girgis@nyspi.columbia.edu.

Copyright

(Copyright © 2019, Elsevier Publishing)

DOI

10.1016/j.pscychresns.2019.04.003

PMID

30991249

Abstract

We previously demonstrated that violent ideation predicts both violent acts and eventual progression to syndromal psychosis in individuals at clinical high-risk for psychosis (CHR). We performed amygdalar surface morphometry analysis on MRI scans from 70 CHR individuals, 21 of whom had violent ideation, 49 of whom did not. CHR individuals with violent ideation have abnormal and asymmetric amygdalar volumes. These data suggest some commonalities in the genesis of violence and aggression among clinical populations, as well as that there may be specific neurobiological links between violence and psychosis.

Copyright © 2019 Elsevier B.V. All rights reserved.

Language: en

Keywords

Amygdala; Clinical high-risk; Ideation; MRI; Psychosis; Violence