Citation

Yang J, He G, Chen S, Pan Z, Zhang J, Li Y, Lyu J. Eur. J. Surg. Oncol. 2019; ePub(ePub): ePub.

Affiliation

Clinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China; School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China; Institute of Evidence-Based Medicine and Knowledge Translation, Henan University, Kaifeng, China. Electronic address: lujun2006@xjtu.edu.cn.

Copyright

(Copyright © 2019, Elsevier Publishing)

DOI

10.1016/j.ejso.2019.03.022

PMID

30914288

Abstract

BACKGROUND: A diagnosis of cancer is associated with increased risks of suicidal ideation and suicide attempts. Genital-system cancer comprises nearly a third of all cancers in males. We used the SEER database to identify the incidence of and risk factors for suicide death in male patients with genital-system cancer in the United States.

METHOD: Patients were selected from the SEER database, and X-tile software was used to find the best cutoffs for stratifying age. Logistic regression was used to identify independent risk factors for suicide death. Only variables that were statistically significant in the univariate logistic regression models were analyzed in multivariate logistic regression models.

RESULT: This study found that age (18-66 vs ≥ 76 years: OR = 3.300, P < 0.001; 67-75 vs ≥ 76 years: OR = 1.832, P < 0.001), being unmarried (OR = 1.332, P = 0.010), being divorced, separated, or widowed (OR = 1.338, P = 0.002), caucasian (OR = 2.074, P = 0.003) and not receiving surgery or having an unknown surgery status (OR = 1.405, P < 0.001) significantly increased the risk of suicide death. A particularly important finding was that a time of <1 year after the diagnosis was related to an increased risk of suicide death (<1 vs ≥ 10 years: OR = 1.761, P = 0.008).

CONCLUSION: We found that a number of factors significantly increased the risk of suicide. Importantly, a time of <1 year after the diagnosis was related to an increased risk of suicide death, which indicates the importance of identifying and treating people at risk of suicide as early as possible. These can help clinicians to understand suicidal patients and provide them with appropriate support.

Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.

Language: en

Keywords

Genital-system cancer; Incidence; Risk factors; SEER; Suicide