Citation

McCrory E, Ogle JR, Gerin MI, Viding E. Child Maltreat. 2019; ePub(ePub): 1077559519830524.

Affiliation

University College London, London, United Kingdom.

Copyright

(Copyright © 2019, American Professional Society on the Abuse of Children, Publisher SAGE Publishing)

DOI

10.1177/1077559519830524

PMID

30897955

Abstract

Childhood maltreatment is associated with a lifetime increase in risk of mental health disorder. We propose that such vulnerability may stem in large part from altered patterns of social functioning. Here, we highlight key findings from the psychological and epidemiological literature indicating that early maltreatment experience compromises social functioning and attenuates social support in ways that increase mental health vulnerability. We then review the extant neuroimaging studies of children and adolescents, focusing on three domains implicated in social functioning: threat processing, reward processing, and emotion regulation. We discuss how adaptations in these domains may increase latent vulnerability to mental health problems by impacting on social functioning via increased stress susceptibility as well as increased stress generation. Finally, we explore how computational psychiatry approaches, alongside systematically reported measures of social functioning, can complement studies of neural function in the creation of a mechanistic framework aimed at informing approaches to prevention and intervention.

Language: en

Keywords

brain; computational psychiatry; maltreatment; psychiatric disorder; social functioning