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Abstract
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OBJECTIVE To investigate the incidence of suicidal ideation and its influencing factors in patients with major depressive disorder.
METHODS Beck scale for suicidal ideation (SSI) was used to evaluate the suicidal ideation of 155 patients with major depressive disorder. The self-made general data questionnaire collected demographic data and used 17 Hamilton depression scale (HAMD-17) and Hamilton anxiety scale (HAMA) to evaluate the factors affecting suicidal ideation. The incidence of suicidal ideation in patients with major depressive disorder was 49.7% (77/155), and that in patients with history of suicide attempt was 17.4% (27/155). Compared with non-Han patients, Han suicidal ideation was stronger (P<0.05). Compared with patients without suicide attempt, patients with suicide attempt had a stronger suicidal ideation (P<0.05); compared with non-suicidal group, HAMD total score, anxiety/somatic factor score, cognition The scores of barrier factors and retardation factors were higher (P<0.05). Path analysis showed that depression (β=0.22, P<0.01), history of attempted suicide (β=0.41, P<0.01) and suspected disease (β= -0.21, P<0.01) has suicidal ideation Predictive effects, anxiety (β=0.08, P<0.01) and suspected disease (β=0.07, P<0.01) all have an indirect effect on suicidal ideation through depression. Bootstrap BC mediation effect test shows that depression in anxiety versus suicidal ideation The effect is completely mediating, and it plays a part in mediating the influence of suspected suicidal ideation.
CONCLUSION The incidence of suicidal ideation in patients with major depressive disorder is high, and the history of suicide attempt and the severity of depression are the main dangers of suicidal ideation. Factors, in the suicide prevention work should pay more attention to patients with suicide attempt and serious depression.
目的 探讨重性抑郁障碍患者中自杀意念的发生率及其影响因素.方法 使用贝克自杀意念量表(Beck scale for suicidal ideation,SSI)对155例重性抑郁障碍患者评估有无自杀意念,并使用自制的一般资料调查问卷收集人口学资料,使用17项汉密尔顿抑郁量表(Hamilton depression scale,HAMD-17)和汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)对患者进行自杀意念影响因素的评估.结果 重性抑郁障碍患者自杀意念的发生率为49.7％(77/155),有自杀未遂史的患者为17.4％(27/155).相对于非汉族患者,汉族患者自杀意念更强(P<0.05);相对于无自杀未遂史患者,有自杀未遂史患者自杀意念更强(P<0.05);与无自杀意念组比较,有自杀意念患者的HAMD总分、焦虑/躯体化因子分、认知障碍因子分、阻滞因子分更高(P<0.05).路径分析结果表明,抑郁(β=0.22,P<0.01)、自杀未遂史(β=0.41,P<0.01)和疑病(β=-0.21,P<0.01)对自杀意念具有直接预测作用,焦虑(β=0.08,P<0.01)和疑病(β=0.07,P<0.01)皆通过抑郁对自杀意念起间接作用.Bootstrap BC中介效应检验显示,抑郁在焦虑对自杀意念的影响中起完全中介作用,在疑病对自杀意念的影响中起部分中介作用.结论 重性抑郁障碍患者自杀意念的发生率较高,有自杀未遂史和抑郁情绪严重程度是自杀意念主要的危险因素,在自杀预防工作中要多关注有自杀未遂史和严重抑郁情绪的患者.
Language: zh |