Citation

Kreitzer NP, Hart K, Lindsell CJ, Manley GT, Dikmen SS, Ratcliff JJ, Yue JK, Adeoye OM. J. Head Trauma Rehabil. 2019; 34(3): E10-E17.

Affiliation

Department of Emergency Medicine (Drs Kreitzer and Adeoye), Division of Neurocritical Care (Drs Kreitzer and Adeoye), and Department of Neurosurgery (Dr Adeoye), University of Cincinnati, Cincinnati, Ohio; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee (Ms Hart and Dr Lindsell); Department of Neurological Surgery, University of California, San Francisco (Drs Manley and Yue); Department of Rehabilitation Medicine, University of Washington, Seattle (Dr Dikmen); Department of Emergency Medicine, and Department of Neurology, Division of Neurocritical Care Emory University, Atlanta, Georgia (Dr Ratcliff).

Copyright

(Copyright © 2019, Lippincott Williams and Wilkins)

DOI

10.1097/HTR.0000000000000457

PMID

30499935

Abstract

OBJECTIVE: To evaluate the relationship between satisfaction with life (SWL) and functional outcome after traumatic brain injury (TBI). SETTING AND PARTICIPANTS: The Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot study (TRACK-TBI Pilot) enrolled patients at 3 US Level I trauma centers within 24 hours of TBI.

DESIGN: Patients were grouped by outcome measure concordance (good-recovery/good-satisfaction, impaired-recovery/impaired-satisfaction) and discordance (good-recovery/impaired-satisfaction, impaired-recovery/good-satisfaction). Logistic regression was utilized to determine predictors of discordance. MAIN MEASURES: Functional outcome: Glasgow Outcome Scale-Extended (GOSE); SWL: Satisfaction with Life Scale (SWLS).

RESULTS: Of the 586 enrolled subjects, 298 had completed both outcome measures at 6-month follow-up; the correlation between GOSE and SWLS was 0.380. Patients with impaired-recovery (GOSE < 7)/impaired-satisfaction (SWLS < 20) were more likely to have mild TBI (83% vs 62%, P =.012), baseline depression (42% vs 15%, P <.0001), and 6-month depression (59% vs 21%, P <.0001) when compared with patients with impaired-recovery/good-satisfaction. Patients with good-recovery/impaired-satisfaction were more likely to have baseline depression (31% vs 13%, P <.0001) and 6-month depression (33% vs 6%, P <.0001) compared with good-recovery/good-satisfaction.

CONCLUSION: Correlation between SWL and functional outcome was not strong, and depression may modulate the association. Future research should account for functional, mental health, and patient-centered outcomes when assessing TBI recovery.

Language: en