Citation

Strain JJ. World J. Biol. Psychiatry 2018; 19(Suppl 1): S14-S20.

Affiliation

a Department of Psychiatry , Icahn School of Medicine at Mount Sinai , New York , NY , USA.

Copyright

(Copyright © 2018, World Federation of the Societies of Biological Psychiatry, Publisher Informa - Taylor and Francis Group)

DOI

10.1080/15622975.2018.1459049

PMID

30204561

Abstract

OBJECTIVES: This paper focuses on the psychobiology of stress, depression, adjustment disorders (ADs), and resilience. Since the ADs fall under the rubric in DSM-5 of Trauma and Stressor-Related Disorders, essentials of the psychobiology of stress-response syndromes will be reviewed.

METHODS: A narrative review of the psychobiology of stress-response syndromes is undertaken, and the implications for our understanding of ADs are discussed.

RESULTS: Advances in our understanding of the psychobiology of stress-response syndromes provide an important foundation for understanding ADs, and for conceptualizing their diagnosis, as well as issues of resilience.

CONCLUSIONS: Future investigations of the psychobiology of trauma- and stressor-related disorders may shed additional light on ADs, and ultimately improve their treatment.

Language: en

Keywords

Adjustment disorder; allostatic load; psychobiology of stress; stress response; stress-related disorder