Citation

Creswell KG, Chung T. Alcohol Clin. Exp. Res. 2018; 42(10): 1874-1879.

Affiliation

Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O'Hara Street, Pittsburgh, Pennsylvania, 15213.

Copyright

(Copyright © 2018, John Wiley and Sons)

DOI

10.1111/acer.13846

PMID

30047988

Abstract

An emerging framework for multimodal assessment of addictions (Kwako et al., 2016), and expanded definitions of acceptable endpoints for alcohol treatment trials (Food and Drug Administration, 2006) are informing efforts toward personalized treatment of alcohol use disorder (AUD). A critical issue in determining for whom an intervention will work lies in the definition of clinical trial endpoints. The six articles in this virtual issue of Alcoholism: Clinical and Experimental Research illustrate recent progress in identifying predictors of alcohol treatment outcome, and pioneering work on the stability and validity of promising non-abstinent (e.g., low-risk drinking) clinical trial endpoints. As a set, the articles highlight how definitions of AUD treatment outcomes or trial end-points can influence the identification of predictors of clinical course. This article is protected by copyright. All rights reserved.

This article is protected by copyright. All rights reserved.

Language: en