Citation

Iwata M, Iwamoto K, Kawano N, Kawaue T, Ozaki N. Psychiatry Clin. Neurosci. 2018; 72(10): 747-773.

Affiliation

Department of Psychiatry, Nagoya University, Graduate School of Medicine, Nagoya, Aichi, 466-8550, Japan.

Copyright

(Copyright © 2018, John Wiley and Sons)

DOI

10.1111/pcn.12734

PMID

29962103

Abstract

AIM: Although automobile driving is necessary for many people, including patients with mental disorders, the influence of psychotropic drugs on driving performance remains unclear and requires scientific verification. Therefore, the objective of this study was to conduct a review of the literature in order to aid the development of a valid evaluation method regarding the influence of medication on driving performance.

METHODS: We conducted a literature search using the two sets of terms on PubMed. One set was related to psychotropic drugs, and the other to driving tests. We excluded reviews and case studies and added literature found on other sites.

RESULTS: A total of 121 relevant literatures were found. The experiments were roughly divided into on-the-road tests (ORTs) or driving simulators (DSs). Although highway driving test in ORTs are most often used to evaluate driving performance, DSs are becoming increasingly common because of their safety and low cost. The validity of evaluation methods for alcohol should be verified; however, we found that there were few validated tests, especially for DSs. The scenarios and measurement indices of each DS were different, which makes it difficult to compare the results of DS studies directly. No evaluation indices, except for standard deviation of lateral position, were sufficiently validated.

CONCLUSIONS: Although highway ORTs are the gold standard, DSs were shown to have an increasing role in evaluating driving performance. DSs need to be established a reliability and validated with alcohol to accumulate more high-quality evidence. This article is protected by copyright. All rights reserved.

This article is protected by copyright. All rights reserved.

Language: en

Keywords

driving performance; driving simulator; measurement of driving; on-the-road test; psychotropic drug