Citation

Zhang C, Deng K, Guo Y, Wang Z, Yu G. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017; 31(7): 885-889.

Affiliation

Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan Hubei, 430071, P.R.China.yuguorong195505@126.com.

Copyright

(Copyright © 2017, Zhongguo Xiufu Chongjian Waike Zazhi Bianjibu)

DOI

10.7507/1002-1892.201612048

PMID

29798537

Abstract

OBJECTIVE: To review the current status and advances of the correlation between traumatic brain injury (TBI) and fracture healing.

METHODS: The related domestic and abroad literature about the correlation between TBI and fracture healing was extensively reviewed and analyzed.

RESULTS: There are a variety of studies on the correlation between TBI and fracture healing, which can be divided into two major aspects: revascularization and osteogenesis; the local and systemic changes of the neuropeptide and hormone after TBI.

CONCLUSION: TBI facilitates callus formation, the further research is needed to clarify the exact mechanism.

Language: zh

Vernacular Abstract

目的: 总结创伤性脑外伤（traumatic brain injury，TBI）对骨折愈合影响机制研究的进展。.

方法: 广泛查阅国内外有关 TBI 对骨折愈合影响的文献，并进行总结分析。.

结果: TBI 影响骨折愈合机制复杂，研究方向可大致分为骨折愈合过程中血管生成及骨再生的调节，以及脑外伤后神经肽及相关激素反应后的局部和全身变化。.

结论: TBI 对骨折愈合起促进作用，其确切作用机制有待进一步研究。.

Language: zh

Keywords

Traumatic brain injury; fracture healing; mechanism