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Abstract
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The aim of the paper was to study
frequency of laboratory determinations
and toxicological information
related to over-the-counter drugs
(OTC): paracetamol (acetaminophen),
salicylates and dextromethorphan.
The research was based on data from
Toxicological Laboratory and Poison
Information Center UJ CM in Krakow
in years 2010-2015.
Paracetamol was determined averagely
102 times a year, more than
50% (57 cases) were positive with
confirmation of poisoning. The least
number of paracetamol poisoning
was noted in 2011 (35 cases), the
most were in 2015 (98 cases). In the
time span there were averagely 40
salicylates check measurements
a year, less than 50% (15 cases) were
positive.
Dextromethorphane was confirmed
averagely in 31 patients a year,
decrease of the drug intoxications
was noted in 2013-2015. Paracetamol
and dextromethorphan were the most
often the cause of poisoning in group
of patients 13-18 years old, salicylates
- more than 30 years. In the group of
small children there were only a few
poisonings with paracetamol.
Toxicological information data
related to paracetamol, salicylates
and dextromethorphan were similar
to data from toxicological laboratory.
Mean year numbers of drug
poisoning information were: 90 (paracetamol),
14 (salicylates), 30 (dextromethorphan).
The differences were in patients
age distribution. Acute poisonings
with OTC were related mainly to
paracetamol, young patients (13-
18 years) and young adults (19-29
years). Salicylates poisoning information
were related mainly to the
group of adult patients (> 30 years),
dextromethorphan was abused mainly by oung patients
(13-18 years). There were no observed poisonings with
salicylates and dextromethorphan in children, but there
were toxicological information about paracetamol and salicylates
poisoning and overdose in group of children (1-6
years).
Language: pl |