Citation

Tikàsz A, Potvin S, Richard-Devantoy S, Lipp O, Hodgins S, Lalonde P, Lungu O, Dumais A. Schizophr. Res. 2018; 197: 249-252.

Affiliation

Centre de Recherche de l'Institut Universitaire en Santé Mentale de Montréal, Montreal, Canada; Department of Psychiatry, University of Montreal, Montreal, Canada; Institut Philippe-Pinel de Montréal, Montreal, Canada. Electronic address: alexandre.dumais@umontreal.ca.

Copyright

(Copyright © 2018, Elsevier Publishing)

DOI

10.1016/j.schres.2017.11.011

PMID

29129509

Abstract

We investigated the influence of anger processing on cognitive control in male schizophrenia patients presenting violent behaviors. We recruited 23 patients without and 24 patients with (SCZ+V) a history of violent behaviors, as well as 22 healthy non-violent men. Participants were administered an affective (angry-neutral faces) Go/NoGo task while undergoing functional magnetic resonance imaging. We found a reduced activation in the dorsolateral prefrontal cortex in SCZ+V patients specifically when inhibiting a response while viewing angry faces. These results show an inability of SCZ+V to recruit a core region of the (inhibitory) cognitive control network in the context of anger.

Copyright © 2017 Elsevier B.V. All rights reserved.

Language: en

Keywords

Anger; Cognitive control; Go/NoGo; Schizophrenia; Violence; fMRI