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Journal Article

Citation

Yoon BH, Angst J, Bahk WM, Wang HR, Bae SO, Kim MD, Jung YE, Min KJ, Lee HB, Won S, Hong J, Choi MS, Jon DI, Woo YS. Clin. Psychopharmacol. Neurosci. 2017; 15(4): 352-360.

Affiliation

Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Copyright

(Copyright © 2017, Korean College of Neuropsychopharmacology)

DOI

10.9758/cpn.2017.15.4.352

PMID

29073747

Abstract

OBJECTIVE: The aim of this study was to examine the validity of the Korean version of the Hypomania Checklist-32, second revision (HCL-32-R2) in mood disorder patients.

METHODS: A total of 454 patients who diagnosed as mood disorder according to Structured Clinical Interview for DSM-IV Axis I Disorders, clinician version (SCID-CV) (bipolar disorder [BD] I, n=190; BD-II, n=72; and major depressive disorder [MDD], n=192) completed the Korean module of the HCL-32-R2 (KHCL-32-R2).

RESULTS: The KHCL-32-R2 showed a three-factorial structure (eigenvalue >2) that accounted for 43.26% of the total variance. Factor 1 was labeled "active/elated" and included 16 items; factor 2, "irritable/distractible" and included 9 items; and factor 3 was labeled "risk-taking/indulging" and included 9 items. A score of 16 or more on the KHCL-32-R2 total scale score distinguished between BD and MDD, which yielded a sensitivity of 70% and a specificity of 70%. MDD and BD-II also could be differentiated at a cut-off of 15 with maximized sensitivity (0.67) and specificity (0.66). Cronbach's alpha of KHCL-32-R2 and its subsets (factors 1, 2, and 3) were 0.91, 0.89, 0.81 and 0.79, respectively. Correlations between KHCL-32-R2 and Montgomery- Asberg Depression Rating Scale, Young Mania Rating Scale and Korean version of Mood Disorder Questionnaire were -0.66 (p=0.41), -0.14 (p=0.9), and 0.61 (p<0.001), respectively.

CONCLUSION: The KHCL-32-R2 may be a useful tool in distinguishing between bipolar and depressive patients in clinical settings.


Language: en

Keywords

Bipolar disorder; HCL-32-R2; Major depression.; Sensitivity; Specificity; Validation

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