Citation

Usuda K, Nishi D, Okazaki E, Makino M, Sano Y. Psychiatry Clin. Neurosci. 2017; 71(12): 836-842.

Affiliation

Toda Chuo Women's Hospital, Saitama, Japan.

Copyright

(Copyright © 2017, John Wiley and Sons)

DOI

10.1111/pcn.12562

PMID

28767198

Abstract

AIM: Depression during pregnancy adversely affects both mother and child. As antenatal depression is a predictor of postnatal depression, early detection might prevent postnatal depression. The Edinburgh Postnatal Depression Scale (EPDS) is frequently used during the perinatal period, but the cut-off score during pregnancy has not been verified for the Japanese population. We aimed to clarify the optimal EPDS cut-off score in mid-pregnancy in Japan.

METHODS: We recruited pregnant women aged 20 years or older at 12-24 weeks of gestation and those who scored ≥ 9 on the EPDS were invited to participate in this study. In parallel with the EPDS, the Japanese version of the Mini-International Neuropsychiatric Interview was administered to determine diagnosis of major depression episode (MDE). We then calculated the receiver operating characteristic curve, sensitivity and specificity, and positive and negative predictive values for the EPDS.

RESULT: All 210 participants were in the second trimester except for one (12 weeks of gestation). Twenty participants were diagnosed with MDE. With a cut-off score set at 13 points, the area under the curve was 0.956; sensitivity and specificity were 90.0% and 79.0%, respectively; and positive and negative predictive values were 54.5% and 98.9%, respectively.

CONCLUSION: To our knowledge, this is the first study to clarify the optimal EPDS cut-off score in the second trimester for Japan. This finding will be helpful for appropriate screening for antenatal depression in Japan.

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Language: en

Keywords

Edinburgh Postnatal Depression Scale (EPDS); cut-off score; screening; second trimester; validity