Citation

Stephens JA, Salorio CF, Barber AD, Risen SR, Mostofsky SH, Suskauer SJ. Dev. Neurorehabil. 2018; 21(7): 423-430.

Affiliation

e Department of Pediatrics , Johns Hopkins School of Medicine , Baltimore , MD , USA.

Copyright

(Copyright © 2018, Informa - Taylor and Francis Group)

DOI

10.1080/17518423.2017.1338777

PMID

28692408

Abstract

PURPOSE AND METHOD: This study examined functional connectivity of the default mode network (DMN) and examined brain-behavior relationships in a pilot cohort of children with chronic mild to moderate traumatic brain injury (TBI).

RESULTS: Compared to uninjured peers, children with TBI demonstrated less anti-correlated functional connectivity between DMN and right Brodmann Area 40 (BA 40). In children with TBI, more anomalous less anti-correlated) connectivity between DMN and right BA 40 was linked to poorer performance on response inhibition tasks.

CONCLUSION: Collectively, these preliminary findings suggest that functional connectivity between DMN and BA 40 may relate to longterm functional outcomes in chronic pediatric TBI.

Language: en

Keywords

Functional neuroimaging; mild traumatic brain injury; moderate traumatic brain injury; neural networks; response inhibition