|
Citation
|
Guo L, Xu Y, Deng J, Gao X, Huang G, Huang J, Deng X, Zhang WH, Lu C. Addiction 2017; 112(9): 1600-1609. |
|
Affiliation
|
Department of Medical statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, People's Republic of China. |
|
Abstract
|
AIMS: To test, among Chinese adolescents: (1) whether childhood maltreatment is associated with non-medical use of prescription drugs (NMUPD), (2) whether there are interaction effects of childhood maltreatment and depressive symptoms on NMUPD.
DESIGN: A secondary analysis of the cross-sectional data collected from 7(th) and 12(th) graders who were sampled using a multistage, stratified cluster, random sampling method in the 2015 School-based Chinese Adolescents Health Survey (SCAHS). SETTING: Surveys conducted in high schools in six cities of China in 2015. PARTICIPANTS: There were 24,457 students who were invited to participate and 23,039 students' questionnaires were completed and qualified for our survey. MEASUREMENTS: The outcomes comprised self-report of NMUPD (prior 30 days); a history of childhood maltreatment was our main predictor; other covariates included depressive symptoms, smoking, drinking, and demographics. Data were analyzed using multi-level regression modeling.
FINDINGS: Our final multivariable logistic regression models demonstrated that after adjusting for other variables, physical abuse was positively associated with non-medical use of opioids (adjusted odds ratio [AOR] = 1.13, 95% confidence interval [CI] = 1.10-1.22), sedatives (AOR = 1.11, 95% CI = 1.10-1.21), and any prescription drugs (AOR = 1.13, 95% CI = 1.09-1.20); emotional abuse, sexual abuse, and emotional neglect were also associated with an increased risk of opioids misuse, sedatives misuse, and any prescription drugs misuse; students who reported that they had experienced childhood physical neglect were more likely to be involved in the non-medical use of sedatives (AOR = 1.08, 95% CI = 1.04-1.12) and any prescription drugs (AOR = 1.06, 95% CI = 1.03-1.10). Additionally, there was no evidence of interaction effects on NMUPD between depressive symptoms and each of physical abuse, emotional abuse, sexual abuse, physical neglect, and emotional neglect, respectively. .
CONCLUSIONS: Maltreatment while a child is associated with an increased risk of non-medical use of prescription drugs (NMUPD) among Chinese adolescents. The interactions of maltreatment while a child and depressive symptoms do not appear to be significantly associated with NMUPD among Chinese adolescents.
This article is protected by copyright. All rights reserved.
Language: en |