Citation

Jackson R, Logue BA. Anal. Chim. Acta 2017; 960: 18-39.

Affiliation

Department of Chemistry and Biochemistry, South Dakota State University, Box 2202, Brookings, SD, 57007, USA. Electronic address: brian.logue@sdstate.edu.

Copyright

(Copyright © 2017, Elsevier Publishing)

DOI

10.1016/j.aca.2016.12.039

PMID

28193360

Abstract

Although commonly known as a highly toxic chemical, cyanide is also an essential reagent for many industrial processes in areas such as mining, electroplating and synthetic fiber production. The "heavy" use of cyanide in these industries, along with its necessary transportation, increases the possibility of human exposure. Another relatively common, but consistently overlooked, mode of cyanide exposure is inhalation of fire smoke. Both civilians and fire rescue personnel risk exposure during the unfortunate event of a structure fire. Additionally, fire rescue personnel risk long-term effects of habitual exposure throughout their careers in fire rescue. The relatively rapid onset of cyanide toxicity and the fact that cyanide exposure symptoms mimic other medical conditions necessitate a rapid, sensitive, portable, and accurate method for the diagnosis of cyanide exposure. This review focuses on the important issues concerning accurate point-of-care diagnosis of cyanide exposure and cyanide detection technologies that may allow a commercial cyanide exposure diagnostic to become a reality.

Copyright © 2017 Elsevier B.V. All rights reserved.

Language: en

Keywords

Bioanalysis; Cyanide detection; Cyanide poisoning diagnosis; Sensor