Citation

Sen N. Neurochem. Int. 2017; 111: 103-107.

Affiliation

Department of Neuroscience and Regenerative Medicine, Augusta University, 1120 15th Street, CA 2018, Augusta, GA 30907, USA. Electronic address: nsen@augusta.edu.

Copyright

(Copyright © 2017, Elsevier Publishing)

DOI

10.1016/j.neuint.2017.01.019

PMID

28163060

Abstract

Traumatic brain injury (TBI) is one of the major cause of morbidity and mortality and it affects more than 1.7 million Americans each year. Depending on its location and severity, TBI leads to structural and functional damage in several parts of the brain such as cranial nerves, optic nerve tract or other circuitry involved in vision, and occipital lobe. As a result, the function associated with vision processing and perception are significantly affected and cause blurred vision, double vision, decreased peripheral vision and blindness. In this mini-review, we will focus the recent progress made to understand the pathology and underlying cellular/molecular mechanisms involved in the impairment of the integrity of visual systems following TBI.

Copyright © 2017 Elsevier Ltd. All rights reserved.

Language: en