Citation

Pine DS, Trautman PD, Shaffer D, Cohen L, Davies M, Stanley M, Parsons B. Am. J. Psychiatry 1995; 152(6): 923-925.

Affiliation

Division of Child and Adolescent Psychiatry, College of Physicians and Surgeons of Columbia-Presbyterian Medical Center, New York, NY 10032, USA.

Copyright

(Copyright © 1995, American Psychiatric Association)

DOI

unavailable

PMID

7755125

Abstract

OBJECTIVE: This study was designed to determine the seasonality of serotonin functions among adolescents who attempt suicide. METHOD: Platelet [3H]imipramine binding was assessed over a period of 18 months in 98 adolescents who attempted suicide and a comparison group of 23 never-suicidal youths with conduct disorder. RESULTS: [3H]Imipramine (Bmax) was uncorrelated with age, but showed considerable seasonal variability over time in those who had attempted suicide. CONCLUSIONS: [3H]Imipramine binding density in adolescents who attempted suicide exhibited significant seasonality, reaching a nadir in late winter/early spring.

Language: en