Citation

Blair RJ, Veroude K, Buitelaar JK. Neurosci. Biobehav. Rev. 2016; ePub(ePub): ePub.

Affiliation

Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands; Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands.

Copyright

(Copyright © 2016, Elsevier Publishing)

DOI

10.1016/j.neubiorev.2016.10.022

PMID

27794436

Abstract

In this paper, we review fMRI work on neuro-cognitive systems that are considered to be dysfunctional in individuals with conduct problems (i.e., individuals with Conduct Disorder (CD), Oppositional Defiant Disorder (ODD) or antisocial behavior without formal clinical diagnosis). These are: empathy, the acute threat response, reinforcement-based decision-making, response inhibition and the Default Mode Network. Evidence regarding the Default Mode Network is somewhat inconsistent and its functional role/the symptom sets consequent on its dysfunction remain underspecified. However, dysfunctions in the other four neuro-cognitive systems are associated with symptom sets seen in individuals with conduct problems.

Copyright © 2016. Published by Elsevier Ltd.

Language: en