Citation

van der Weiden RM, Helmerhorst FM, Eriksson T. BMJ Case Rep. 2016; 2016(ePub): ePub.

Affiliation

The Biological Psychiatry Research Group, Department of Clinical Sciences, Lund University, Lund, Sweden.

Copyright

(Copyright © 2016, BMJ Publishing Group)

DOI

10.1136/bcr-2016-216378

PMID

27655876

Abstract

Aggression in patients with autism spectrum disorder (ASD) presents an important therapeutic challenge. Conventional treatment appears to be inadequate in a number of cases. The occurrence of severe aggressive symptoms since the inception of adolescence in a male patient with ASD suggested a hormonal influence by androgens. Conventional treatment with antipsychotic and antiepileptic drugs and benzodiazepines was ineffective. A subcutaneous long-acting gonadotropin-releasing hormone agonist (GnRH agonist) injection was given on a monthly basis resulting in a substantial improvement in his aggressive behaviour and renewed socialisation.

2016 BMJ Publishing Group Ltd.

Language: en