Citation

Lopez MC, Ungaro RF, Baker HV, Moldawer LL, Robertson A, Abbott M, Roberts SM, Grattan LM, Morris JG. Harmful Algae 2016; 57(B): 35-38.

Affiliation

Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610; Department of Medicine, College of Medicine, Emerging Pathogens Institute, University of Florida, 2055 Mowry Road; Box 100009, Gainesville, FL 32610.

Copyright

(Copyright © 2016, Elsevier Publishing)

DOI

10.1016/j.hal.2016.03.009

PMID

27594814

Abstract

Ciguatera fish poisoning (ciguatera) is a common clinical syndrome in areas where there is dependence on tropical reef fish for food. A subset of patients develops recurrent and, in some instances, chronic symptoms, which may result in substantial disability. To identify possible biomarkers for recurrent/chronic disease, and to explore correlations with immune gene expression, peripheral blood leukocyte gene expression in 10 ciguatera patients (7 recurrent, 3 acute) from the U.S. Virgin Islands, and 5 unexposed Florida controls were evaluated. Significant differences in gene expression were noted when comparing ciguatera patients and controls; however, it was not possible to differentiate between patients with acute and recurrent disease, possibly due to the small sample sizes involved.

Language: en