Citation

Osterhoff G, Morgan EF, Shefelbine SJ, Karim L, McNamara LM, Augat P. Injury 2016; 47 Suppl 2: S11-20.

Affiliation

Institute of Biomechanics, Trauma Center Murnau, Murnau, Germany; Paracelsus Medical University Salzburg, Salzburg, Austria. Electronic address: biomechanik@bgu-murnau.de.

Copyright

(Copyright © 2016, Elsevier Publishing)

DOI

10.1016/S0020-1383(16)47003-8

PMID

27338221

Abstract

This review will define the role of collagen and within-bone heterogeneity and elaborate the importance of trabecular and cortical architecture with regard to their effect on the mechanical strength of bone. For each of these factors, the changes seen with osteoporosis and ageing will be described and how they can compromise strength and eventually lead to bone fragility.

© 2016 Elsevier Ltd. All rights reserved.

Language: en