Citation

Naimi TS, Stockwell T, Zhao J, Xuan Z, Dangardt F, Saitz R, Liang W, Chikritzhs T. Addiction 2016; 112(2): 207-214.

Affiliation

National Drug Research Institute, Curtin University, Perth, Australia.

Copyright

(Copyright © 2016, John Wiley and Sons)

DOI

10.1111/add.13451

PMID

27316346

Abstract

Selection biases may lead to systematic overestimate of protective effects from 'moderate' alcohol consumption. Overall, most sources of selection bias favor low-volume drinkers Gaetanoers in relation to non-drinkers. Studies that attempt to address these types of bias generally find attenuated or non-significant relationships between low-volume alcohol consumption and cardiovascular disease, which is the major source of possible protective effects on mortality from low-volume consumption. Furthermore, observed mortality effects among established low-volume consumers are of limited relevance to health-related decisions about whether to initiate consumption or to continue drinking purposefully into old age. Short of randomized trials with mortality end-points, there are a number of approaches that can minimize selection bias involving low-volume alcohol consumption.

© 2016 Society for the Study of Addiction.

Language: en