Citation

Wang K, Cui D, Gao L. Front. Biosci. 2016; 21: 890-899.

Affiliation

Neurosurgical Department, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China, lianggaoh@sina.com.

Copyright

(Copyright © 2016, Frontiers in Bioscience)

DOI

unavailable

PMID

27100477

Abstract

Traumatic brain injury (TBI) is a critical cause of hospitalization, disability, and death worldwide. The global increase in the incidence of TBI poses a significant socioeconomic burden. Guidelines for the management of acute TBI mostly pertain to emergency treatment. Comprehensive gene expression analysis is currently available for several animal models of TBI, along with enhanced understanding of the molecular mechanisms activated during injury and subsequent recovery. The current review focuses on the characteristics, molecular basis and management of TBI.

Language: en