Citation

Gift TE, Reimherr FW, Marchant BK, Steans TA, Wender PH. J. Nerv. Ment. Dis. 2016; 204(5): 355-363.

Affiliation

*Department of Psychiatry, University of Rochester, Honeoye Falls, NY; †Department of Psychiatry, University of Utah School of Medicine; and ‡Psychiatric and Behavioral Solutions LLC, Salt Lake City, UT.

Copyright

(Copyright © 2016, Lippincott Williams and Wilkins)

DOI

10.1097/NMD.0000000000000470

PMID

27082828

Abstract

Personality disorders (PDs) are commonly found in adults with attention-deficit/hyperactivity disorder (ADHD) and are associated with increased ADHD symptoms and psychosocial impairment. To assess the impact of PDs or personality traits on retention rates in ADHD trials and whether treating ADHD affects the expression of PD, data were analyzed from 2 methylphenidate trials. Assessment of PDs and personality traits included using the Wisconsin Personality Disorders Inventory IV and the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Personality Disorders. Attention-deficit/hyperactivity disorder symptoms were evaluated using the Wender-Reimherr Adult Attention Deficit Disorder Scale. Major findings were that subjects with cluster A, cluster B, passive-aggressive, or more than 1 PD showed more attrition. Subjects dropping out also had more schizoid and narcissistic traits. Attention-deficit/hyperactivity disorder symptoms (p < 0.001) and all personality traits (range, p = 0.03 to p = 0.001) improved, but there was almost no correlation between changes on these 2 measures. Conversely, of 11 Wisconsin Personality Disorders Inventory IV items that improved most, 8 resembled ADHD or oppositional defiant disorder symptoms.

Language: en