Citation

Peterson DS, Horak FB. Physiology (Bethesda) 2016; 31(2): 95-107.

Affiliation

Veterans Affairs Portland Health Care System (VAPORHCS), Portland, Oregon; and Oregon Health & Science University, Department of Neurology, Portland, Oregon.

Copyright

(Copyright © 2016, International Union of Physiological Sciences, American Physiological Society)

DOI

10.1152/physiol.00034.2015

PMID

26889015

Abstract

People with Parkinson's disease exhibit debilitating gait impairments, including gait slowness, increased step variability, and poor postural control. A widespread supraspinal locomotor network including the cortex, cerebellum, basal ganglia, and brain stem contributes to the control of human locomotion, and altered activity of these structures underlies gait dysfunction due to Parkinson's disease.

Language: en