Citation

Hashim A, Parnell N. Toxicol. Int. 2015; 22(1): 158-159.

Affiliation

Digestive Diseases Centre, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom.

Copyright

(Copyright © 2015, Society of Toxicology India)

DOI

10.4103/0971-6580.172262

PMID

26862278

PMCID

PMC4721165

Abstract

Wilson disease is a rare genetic hepatic and neurological disorder of copper accumulation. Trientine is usually used as a second line in the management of patients with this condition. We present a case of a large overdose of Trientine (60 g) resulting in self-limiting dizziness and vomiting with no further clinical sequelae or significant biochemical abnormalities. This case shows that Trientine has a good safety profile and hence could be used as a first line treatment in patients with Wilson's disease who suffer from psychiatric complications and who might be at risk of self-harm.

Language: en