Citation

Isaksson J, Grigorenko EL, Oreland L, af Klinteberg B, Koposov RA, Ruchkin V. Eur. Arch. Psychiatry Clin. Neurosci. 2015; 266(8): 771-773.

Affiliation

Säter Forensic Psychiatric Clinic, Säter, Sweden.

Copyright

(Copyright © 2015, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00406-015-0664-3

PMID

26616837

Abstract

Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania.

Keywords: Juvenile justice .

Language: en