Citation

de Siqueira A, Salvagni FA, Yoshida AS, Gonçalves-Junior V, Calefi AS, Fukushima AR, Spinosa Hde S, Maiorka PC. Res. Vet. Sci. 2015; 102: 142-149.

Affiliation

Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, Brazil.

Copyright

(Copyright © 2015, British Veterinary Association, Publisher Elsevier Publishing)

DOI

10.1016/j.rvsc.2015.08.006

PMID

26412534

Abstract

The intentional and accidental poisoning of animals and people is a threat to public health and safety worldwide. Necropsies and histopathological examinations of 26 cats and 10 dogs poisoned by the carbamates aldicarb and carbofuran, confirmed by thin layer chromatography (TLC) and high performance liquid chromatography with diode-array detector (HPLC-DAD) were analysed, with variable post mortem interval and conservation of the carcass. Biological matrices were collected for toxicological and histopathological analyses. High performance liquid chromatography with diode-array detector (HPLC-DAD) was utilized to detect aldicarb and its metabolites, aldicarb sulphoxide and aldicarb sulphone, and carbofuran. The variable post mortem interval and the method of conservation of the carcass may be harmful to toxicological, necroscopic and histopathological analyses, that should be performed in order to provide reliable evidences to investigate possible poisoning of animals, which is cruel crime, and are usually linked to domestic or social conflict.

Language: en